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EYES-KCS
I love my pug
Vaccines
This is my schedule I use: Well Puppy check
at 7 weeks old by vet. 8 WEEKS-PARVO AND DISTEMPER, 12 WEEKS REPEAT PLUS BORDATELLA AND ADENOVIRUS 2, 16
WEEKS REPEAT.
I give written instuctions
when to give the next vaccines after the first set at 8 weeks. It is important to adhere to that. DO NOT HAVE YOUR VET GIVE VACCINES ANY EARILER THAN 3 WEEKS AFTER
THE FIRST SET AT 8 WEEKS. READ THE INFO BELOW. TOO MANY VACCINES ARE GIVEN
AND MAY CAUSE MORE HARM THAN GOOD. IT
IS ALSO A GOOD IDEA TO KEEP A SMALL BOTTLE OF BENADRYL LIQUID IN YOUR PURSE AT ALL TIMES FOR THAT EMERGENCY THAT NEVER HAPPENS.
IT JUST MIGHT SAVE YOUR DOGGIES LIFE. BEE STINGS, VACCINES, POISONOUS PLANTS ETC.
Do
not take puppy to dog parks until 6 months old.
UC Davis VMTH Canine and Feline Vaccination Guidelines (Revised 11/09)
The UC Davis VMTH vaccination guidelines below have been based on recently published studies and recommendations
made by task forces (including the AAFP/AFM Advisory Panel on Feline Vaccines, AAHA Canine Vaccine Task Force, and the AVMA
Council on Biologic and Therapeutic Agents), which include representatives from academia, private practices, governmental
regulatory bodies, and industry. These groups have evaluated the benefits versus risks of the vaccines currently available
on the market. Interested readers are referred to documents published by these groups for further information (see References
and Resources listed at the end of this document). The document below has been generated by a group of faculty and staff at
UC Davis School of Veterinary Medicine for the purposes of VMTH veterinary student education and as a reference for referring
veterinarians. These are only general guidelines, as the vaccine types recommended and the frequency of vaccination vary depending
on the lifestyle of the pet being vaccinated, i.e. indoor vs outdoor pets, travel plans, kennel/boarding plans, and underlying
disease conditions such as immune-mediated diseases or pre-existing infections such as FIV infection. Because these factors
may change over time, we recommend the vaccination plan for each individual pet be decided by the owner at routine annual
examinations, following a discussion between the veterinarian and the client regarding the animal's lifestyle in the year
ahead. Guidelines for vaccination in shelter situations can be accessed at the Center for Companion Animal Health's shelter
medicine website. A previous history of vaccination reactions in an individual pet will also affect recommendations for vaccination.
For all vaccines given, the product, expiration date, lot number, route and location of injection is documented in the record. It
should also be noted that much research in the area of companion animal vaccinology is required to generate optimal recommendations
for vaccination of dogs and cats. As further research is performed, and as new vaccines become available on the market, this
document will be continuously updated and modified. Canine Vaccination GuidelinesCanine Core Vaccines Core vaccines are recommended for all puppies and dogs with an unknown vaccination history. The diseases
involved have significant morbidity and mortality and are widely distributed, and in general, vaccination results in relatively
good protection from disease. These include vaccines for canine parvovirus (CPV), canine distemper virus (CDV), canine adenovirus
(CAV), and rabies. Canine Parvovirus, Distemper Virus, and Adenovirus-2 Vaccines For initial puppy
vaccination (≤ 16 weeks), one dose of vaccine containing modified live virus (MLV) CPV, CDV, and CAV-2
is recommended every 3-4 weeks from 6-8 weeks of age, with the final booster being given no sooner than 16 weeks of age. For
dogs older than 16 weeks of age, two doses of vaccine containing modified live virus (MLV) CPV, CDV, and CAV-2 given 3-4 weeks
apart are recommended. After a booster at one year, revaccination is recommended every 3 years thereafter, ideally using a
product approved for 3-year administration, unless there are special circumstances that warrant more or less frequent revaccination.
Note that recommendations for killed parvovirus vaccines and recombinant CDV vaccines are different from the above. These
vaccines are not currently stocked by our pharmacy or routinely used at the VMTH. We do not recommend vaccination with CAV-1
vaccines, since vaccination with CAV-2 results in immunity to CAV-1, and the use of CAV-2 vaccines results in less frequent
adverse events. Canine Rabies Virus Vaccines In accordance with California state law, we recommend
that puppies receive a single dose of killed rabies vaccine at 16 weeks of age. Adult dogs with unknown vaccination history
should also receive a single dose of killed rabies vaccine. A booster is required one year later, and thereafter, rabies vaccination
should be performed every 3 years using a vaccine approved for 3-year administration. Canine Non-Core Vaccines Non-core vaccines are optional vaccines that should be considered in light of the exposure risk of the
animal, ie. based on geographic distribution and the lifestyle of the pet. Several of the diseases involved are often self-limiting
or respond readily to treatment. Vaccines considered as non-core vaccines are canine parainfluenza virus (CPiV), canine influenza
virus, distemper-measles combination vaccine, Bordetella bronchiseptica, Leptospira spp., and Borrelia burgdorferi. Vaccination
with these vaccines is generally less effective in protecting against disease than vaccination with the core vaccines. Canine
Parainfluenza Virus and Bordetella bronchiseptica These are both agents associated with kennel cough
in dogs. For Bordetella bronchiseptica, intranasal vaccination with live avirulent bacteria is recommended for dogs expected
to board, be shown, or to enter a kennel situation within 6 months of the time of vaccination. We currently stock the intranasal
vaccine containing both B. bronchiseptica and CPiV. For puppies and previously unvaccinated dogs, only one dose of this vaccine
is required (recommendations differ for the parenteral, killed form of this vaccine). Most boarding kennels require that this
vaccine be given within 6 months of boarding; the vaccine should be administered at least one week prior to the anticipated
boarding date for maximum effect. Canine Influenza Virus (CIV) Canine influenza virus (H3N8) emerged
in the United States in greyhounds in Florida in 2003. The virus is now enzootic in many dog populations in Colorado, Florida,
Pennsylvania, New Jersey and New York. The virus causes upper respiratory signs including a cough, nasal discharge, and a
low-grade fever followed by recovery. A small percentage of dogs develop more severe signs in association with hemorrhagic
pneumonia. A vaccine is commercially available, which at the time of writing has a 1-year conditional licensure. Based on
evidence provided by the manufacturer, the vaccine may reduce clinical signs and virus shedding in dogs infected by CIV. It
may be useful for dogs traveling and intermingling with other dog populations in areas where the virus is enzootic. The performance
of the vaccine and its duration of immunity in the field are unknown. At the time of writing, only a few cases of CIV infection
have been documented in northern California and the infection has not been widely documented in the general dog population,
so we do not recommend routine vaccination for dogs expected to board, be shown, or enter a kennel situation within northern
California. Vaccination may have the potential to interfere with the results of serological testing, which in non-endemic
areas are useful to assist diagnosis. The UC Davis VMTH does not stock the CIV vaccine or recommend it for use in dogs residing
solely in northern California. Canine Distemper-Measles Combination Vaccine This vaccine has
been used between 4 and 12 weeks of age to protect dogs against distemper in the face of maternal antibodies directed at CDV.
Protection occurs within 72 hours of vaccination. It is indicated only for use in households/kennels/shelters where CDV is
a recognized problem. Only one dose of the vaccine should be given, after which pups are boostered with the CDV vaccine to
minimize the transfer of anti-measles virus maternal antibodies to pups of the next generation. The AAHA Canine Vaccination
Guidelines state that 'recent unpublished studies have shown that the recombinant CDV vaccine immunizes puppies in the
face of passively acquired maternal antibodies. Therefore, the distemper-measles vaccine is no longer the preferred option'.
The UC Davis VMTH does not stock these vaccines as situations requiring their use do not arise commonly in our hospital population. Canine
Leptospira Vaccines Multiple leptospiral serovars are capable of causing disease in dogs, and minimal
cross-protection is induced by each serovar. Currently available vaccines do not contain all serovars, efficacies against
infection with the targeted serovar are between 50 and 75%, and duration of immunity is probably about 1 year. However, leptospirosis
is not uncommon in Northern Californian dogs with exposure histories involving livestock and areas frequented by wild mammals,
the disease can be fatal or have high morbidity, and also has zoonotic potential. Therefore, we suggest annual vaccination
of dogs living in/visiting rural areas or areas frequented by wildlife with vaccines containing all four leptospiral serovars
(grippotyphosa, pomona, canicola and icterohemorrhagiae), ideally before the rainy season, when disease incidence peaks. The
initial vaccination should be followed by a booster 2-4 weeks later, and the first vaccine be given no earlier than 12 weeks
of age. In general, leptospiral vaccines have been associated with more severe postvaccinal reactions (acute anaphylaxis)
than other vaccines. Whether the recent introduction of vaccines with reduced amounts of foreign protein has reduced this
problem is still unclear. Vaccination of dogs in suburban areas with minimal exposure to farm animals or forested areas is
not recommended. Anecdotally, the incidence of reactions has been greatest in puppies (< 12 weeks of age, and especially
< 9 weeks of age) and small-breed dogs. A careful risk-benefit analysis is recommended before considering vaccination of
small breed dogs at risk of exposure to leptospires. Canine Borrelia burgdorferi (Lyme) Vaccine The incidence of Lyme disease in California is currently considered extremely low. Furthermore, use of the vaccine even
in endemic areas (such as the east coast of the US) has been controversial because of anecdotal reports of vaccine-associated
adverse events. Most infected dogs show no clinical signs, and the majority of dogs contracting Lyme disease respond to treatment
with antimicrobials. Furthermore, prophylaxis may be effectively achieved by preventing exposure to the tick vector. If travel
to endemic areas (ie the east coast) is anticipated, vaccination with the Lyme subunit or OspC/OspA-containing bivalent bacterin
vaccine could be considered, followed by boosters at intervals in line with risk of exposure. The UC Davis VMTH does not stock
the Lyme vaccine or recommend it for use in dogs residing solely in northern California. Other Canine Vaccines Several other canine vaccines are currently available on the market. These are vaccines for canine coronavirus,
Giardia spp., canine adenovirus-1, rattlesnake envenomation, and Porphyromonas vaccine. The reports of the AVMA and
the AAHA canine vaccine task force have listed the first three vaccines as not generally recommended, because 'the diseases
are either of little clinical significance or respond readily to treatment', evidence for efficacy of these vaccines is
minimal, and they may 'produce adverse events with limited benefit'. Currently, information regarding the efficacy
of the canine rattlesnake and Porphyromonas vaccines is insufficient. The UC Davis VMTH does not stock or routinely
recommend use of these four vaccines. Canine Coronavirus Vaccine Infection with canine enteric
coronavirus (CCV) alone has been associated with mild disease only, and only in dogs < 6 weeks of age. It has not been
possible to reproduce the infection experimentally, unless immunosuppressive doses of glucocorticoids are administered. Serum
antibodies do not correlate with resistance to infection, and duration of immunity is unknown. In mixed infections with CCV
and canine parvovirus (CPV), CPV is the major pathogen. Vaccination against CPV therefore protects puppies from disease following
simultaneous infection with both canine enteric coronavirus and CPV. Thus, the UC Davis VMTH does not routinely recommend
vaccination against canine enteric coronavirus and the vaccine is not stocked by our pharmacy. Canine Giardia
spp. Vaccine Approximately 90% of dogs respond to treatment for Giardia infection, most infected dogs
are asymptomatic, and the disease is not usually life-threatening. The vaccine does not prevent infection but may reduce shedding
and clinical signs. The zoonotic potential of Giardia remains unclear. Based on existing evidence, the UC Davis VMTH does
not currently recommend routine vaccination of dogs for Giardia spp, and the vaccine is not stocked by our pharmacy. Canine
Rattlesnake Vaccine The canine rattlesnake vaccine comprises venom components from Crotalus atrox (western diamondback).
Although a rattlesnake vaccine may be potentially useful for dogs that frequently encounter rattlesnakes, currently we are
unable to recommend this vaccine because of insufficient information regarding the efficacy of the vaccine in dogs. Dogs develop
neutralizing antibody titers to C. atrox venom, and may also develop antibody titers to components of other rattlesnake venoms,
but research in this area is ongoing. Owners of vaccinated dogs must still seek veterinary care immediately in the event of
a bite, because 1) the type of snake is often unknown; 2) antibody titers may be overwhelmed in the face of severe envenomation,
and 3) an individual dog may lack sufficient protection depending on its response to the vaccine and the time elapsed since
vaccination. According to the manufacturer, to date, rare vaccinated dogs have died following a bite when there were substantial
delays (12-24 hours) in seeking treatment. Recommendations for booster vaccination are still under development, but it appears
that adequate titers do not persist beyond one year after vaccination. Adverse reactions appear to be low and consistent with
those resulting from vaccination with other products available on the market. The product license is currently conditional
as efficacy and potency have not been fully demonstrated. Based on existing evidence, the UC Davis VMTH does not currently
recommend routine vaccination of dogs for rattlesnake envenomation, and the vaccine is not stocked by our pharmacy. Canine
Porphyromonas Vaccine The canine Porphyromonas vaccine is an inactivated Porphyromonas denticanis, P. gulae
and P. salivosa bacterin. It has been marketed 'as an adjunct to professional dental cleaning, periodontal therapy, and
owner-administrated dental care routines' to prevent periodontitis, as demonstrated by a reduction in bone changes (bone
loss/sclerosis) in mice used as an experimental model. The manufacturer recommends that primary vaccination consist of 2 doses
given subcutaneously 3 weeks apart. The product license is currently conditional as efficacy and potency have not been demonstrated
in dogs. Based on existing evidence, the UC Davis VMTH does not currently recommend routine vaccination of dogs for periodontal
disease with this vaccine, and the vaccine is not stocked by our pharmacy.
Titers and Canine Vaccination
Decisions By Christie Keith By Christie Keith It always happens. As soon as dog owners hear that annual re-vaccination for dogs might not be necessary, they also
hear about something called a titer test. “That’s great,” they say to themselves. “A test I can run
every year to see if my dog’s immunity has gotten low and needs boosting!” It seems like the perfect solution
to worries about over-vaccination. However appealing that idea might be, titer tests can’t
be used in this way. That’s because your dog’s immune system is not a gas tank, vaccines are not gas pumps, and
titer tests are not gas gauges. What Is a Titer Test? A
"titer" is a measurement of how much antibody to a certain virus (or other antigen) is circulating in the blood
at that moment. Titers are usually expressed in a ratio, which is how many times they could dilute the blood before they couldn't
find antibodies anymore. If the lab was able to dilute it two times, and then didn't find any more antibodies, that would
be expressed as a titer of 1:2. If they could dilute it a thousand times before they couldn't find any antibodies, that
would be a titer of 1:1000. It would be wonderful to be able to say that once this ratio dips
below a certain level, it’s time to give another vaccination to “boost” immunity. But that reflects an incorrect
understanding of the immune response. Vaccines don’t inject immunity into a dog. Instead, they stimulate the immune
system to form two kinds of cells, antibodies that fight the current infection, and memory cells that remain behind after
the infection has been eradicated, to pump out more antibodies if the same virus is encountered in the future. Memory cells persist for 20 years or more, and are not increased when the animal is re-vaccinated or re-exposed to
the disease. The detection of antibodies in the bloodstream, which is what a titer test does, tells us that process took place
and that memory cells are present, but the absence of antibodies does not mean there are no memory cells or that the dog is
not immune. Veterinary immunologist Ian Tizard writes, "You can have a negative titer and if the pet is exposed, memory
cells can respond within hours to regenerate enough antibodies for protective immunity." (Tizard, Ian R., Veterinary
Immunology: An Introduction, 6th Ed, Saunders 2000.) What Titer Tests Are Good For
If you can’t “top off” your dog’s immunity to viruses with booster shots,
and you can’t tell from the titer test if his or her immunity is waning, what could a titer test possibly be good for?
It takes up to 14 days for the immune system to complete its response to a modified live virus
vaccination for canine viruses. This process is called “serovonversion,” and in the vaccination stakes, it’s
the brass ring. This means the dog has formed both antibodies and memory cells to those viruses. If you test the dog’s
titer two weeks after vaccination, you can tell if he or she formed immunity to the virus. If,
however, the dog did not seroconvert after vaccination, this lets you know that the vaccine didn’t work; that is, it
did not provoke the formation of immunity. This is usually because the puppy was too young, and his or her mother’s
immunity was still present at a high enough level to prevent successful immunization. (Puppies acquire temporary immunity
from their mothers after birth.) In an adult dog or much older puppy, the reasons that vaccination
fails to provoke immunity are usually related to the use of improperly stored, handled, shipped, or administered vaccines.
Very rarely, the puppy or dog has a defective immune system and is incapable of seroconverting. Titer
tests are also very useful to breeders and the owners of young puppies. They can be used to help you customize an effective
but minimal vaccination program for your puppy. Although a series of vaccines is typically given to puppies, this isn’t
because a series is needed to produce an immune response. It’s done because some puppies don’t form immunity to
the first vaccination, and would be unprotected if the next in the series were not administered. Puppies, like adult dogs,
need just one vaccine that works, what immunologists call a “single immunizing dose.” By checking your puppy’s
titers two weeks after the first vaccinations are given, you can determine whether or not immunity formed. This enables you
to avoid giving further vaccines that will provide no benefit to the puppy if he or she is already immune, as well as let
you know you need to continue to protect your puppy from exposure to these diseases if it turns out he or she did not form
immunity from the first vaccinations. You do not have to wonder, worry, and guess if your puppy’s shots worked; you
can know. The Exceptions to the Rule Titer testing
is usually done in dogs for the most common and deadly canine viruses, parvovirus (CPV) and distemper (CDV). Rabies titer
testing is also done, usually for purposes of travel to foreign countries that require it. Some viruses have unusual antibody
patterns (such as FIP in cats or HIV in humans), but we do not have vaccines for any diseases of this type in dogs. Also,
bacterial antibodies differ from viral antibodies in a number of ways, and bacterial titer testing is typically done in veterinary
medicine as a means of diagnosing acute illness, not monitoring vaccine response or ongoing immunity. Should You Test? So, should you test your dog’s titers? Probably
not. Nearly all previously vaccinated adult dogs are immune to parvovirus and distemper, and the titer test isn’t going
to give you any useful information. You cannot make an immune dog “more immune” to a virus with additional vaccination,
as the previous immunity will wipe out the virus in the vaccine. There will be no increase in immunity and no benefit to the
dog. (Schultz, Ronald D., "Current and future canine and feline vaccination programs", Veterinary Medicine, March
1998.) If a titer test will give you peace of mind, or help you make a vaccination decision about a puppy or a dog of unknown
vaccine history, then it’s worth considering. But for most owners of well-vaccinated adult dogs, neither re-vaccination
nor titer testing for parvovirus and distemper are necessary. It always happens. As soon
as dog owners hear that annual re-vaccination for dogs might not be necessary, they also hear about something called a titer
test. “That’s great,” they say to themselves. “A test I can run every year to see if my dog’s
immunity has gotten low and needs boosting!” It seems like the perfect solution to worries about over-vaccination. However appealing that idea might be, titer tests can’t be used in this way. That’s because your dog’s
immune system is not a gas tank, vaccines are not gas pumps, and titer tests are not gas gauges. What
Is a Titer Test? A "titer" is a measurement of how much antibody to a certain
virus (or other antigen) is circulating in the blood at that moment. Titers are usually expressed in a ratio, which is how
many times they could dilute the blood before they couldn't find antibodies anymore. If the lab was able to dilute it
two times, and then didn't find any more antibodies, that would be expressed as a titer of 1:2. If they could dilute it
a thousand times before they couldn't find any antibodies, that would be a titer of 1:1000. It
would be wonderful to be able to say that once this ratio dips below a certain level, it’s time to give another vaccination
to “boost” immunity. But that reflects an incorrect understanding of the immune response. Vaccines don’t
inject immunity into a dog. Instead, they stimulate the immune system to form two kinds of cells, antibodies that fight the
current infection, and memory cells that remain behind after the infection has been eradicated, to pump out more antibodies
if the same virus is encountered in the future. Memory cells persist for 20 years or more, and
are not increased when the animal is re-vaccinated or re-exposed to the disease. The detection of antibodies in the bloodstream,
which is what a titer test does, tells us that process took place and that memory cells are present, but the absence of antibodies
does not mean there are no memory cells or that the dog is not immune. Veterinary immunologist Ian Tizard writes, "You
can have a negative titer and if the pet is exposed, memory cells can respond within hours to regenerate enough antibodies
for protective immunity." (Tizard, Ian R., Veterinary Immunology: An Introduction, 6th Ed, Saunders 2000.) What Titer Tests Are Good For If you can’t “top off”
your dog’s immunity to viruses with booster shots, and you can’t tell from the titer test if his or her immunity
is waning, what could a titer test possibly be good for? It takes up to 14 days for the immune
system to complete its response to a modified live virus vaccination for canine viruses. This process is called “serovonversion,”
and in the vaccination stakes, it’s the brass ring. This means the dog has formed both antibodies and memory cells to
those viruses. If you test the dog’s titer two weeks after vaccination, you can tell if he or she formed immunity to
the virus. If, however, the dog did not seroconvert after vaccination, this lets you know that
the vaccine didn’t work; that is, it did not provoke the formation of immunity. This is usually because the puppy was
too young, and his or her mother’s immunity was still present at a high enough level to prevent successful immunization.
(Puppies acquire temporary immunity from their mothers after birth.) In an adult dog or much
older puppy, the reasons that vaccination fails to provoke immunity are usually related to the use of improperly stored, handled,
shipped, or administered vaccines. Very rarely, the puppy or dog has a defective immune system and is incapable of seroconverting.
Titer tests are also very useful to breeders and the owners of young puppies. They can be used
to help you customize an effective but minimal vaccination program for your puppy. Although a series of vaccines is typically
given to puppies, this isn’t because a series is needed to produce an immune response. It’s done because some
puppies don’t form immunity to the first vaccination, and would be unprotected if the next in the series were not administered.
Puppies, like adult dogs, need just one vaccine that works, what immunologists call a “single immunizing dose.”
By checking your puppy’s titers two weeks after the first vaccinations are given, you can determine whether or not immunity
formed. This enables you to avoid giving further vaccines that will provide no benefit to the puppy if he or she is already
immune, as well as let you know you need to continue to protect your puppy from exposure to these diseases if it turns out
he or she did not form immunity from the first vaccinations. You do not have to wonder, worry, and guess if your puppy’s
shots worked; you can know. The Exceptions to the Rule Titer
testing is usually done in dogs for the most common and deadly canine viruses, parvovirus (CPV) and distemper (CDV). Rabies
titer testing is also done, usually for purposes of travel to foreign countries that require it. Some viruses have unusual
antibody patterns (such as FIP in cats or HIV in humans), but we do not have vaccines for any diseases of this type in dogs.
Also, bacterial antibodies differ from viral antibodies in a number of ways, and bacterial titer testing is typically done
in veterinary medicine as a means of diagnosing acute illness, not monitoring vaccine response or ongoing immunity. Should You Test? So, should you test your dog’s titers? Probably
not. Nearly all previously vaccinated adult dogs are immune to parvovirus and distemper, and the titer test isn’t going
to give you any useful information. You cannot make an immune dog “more immune” to a virus with additional vaccination,
as the previous immunity will wipe out the virus in the vaccine. There will be no increase in immunity and no benefit to the
dog. (Schultz, Ronald D., "Current and future canine and feline vaccination programs", Veterinary Medicine, March
1998.) If a titer test will give you peace of mind, or help you make a vaccination decision about a puppy or a dog of unknown
vaccine history, then it’s worth considering. But for most owners of well-vaccinated adult dogs, neither re-vaccination
nor titer testing for parvovirus and distemper are necessary. It always happens. As soon as dog
owners hear that annual re-vaccination for dogs might not be necessary, they also hear about something called a titer test.
“That’s great,” they say to themselves. “A test I can run every year to see if my dog’s immunity
has gotten low and needs boosting!” It seems like the perfect solution to worries about over-vaccination. However appealing that idea might be, titer tests can’t be used in this way. That’s because your dog’s
immune system is not a gas tank, vaccines are not gas pumps, and titer tests are not gas gauges. What
Is a Titer Test? A "titer" is a measurement of how much antibody to a certain
virus (or other antigen) is circulating in the blood at that moment. Titers are usually expressed in a ratio, which is how
many times they could dilute the blood before they couldn't find antibodies anymore. If the lab was able to dilute it
two times, and then didn't find any more antibodies, that would be expressed as a titer of 1:2. If they could dilute it
a thousand times before they couldn't find any antibodies, that would be a titer of 1:1000. It
would be wonderful to be able to say that once this ratio dips below a certain level, it’s time to give another vaccination
to “boost” immunity. But that reflects an incorrect understanding of the immune response. Vaccines don’t
inject immunity into a dog. Instead, they stimulate the immune system to form two kinds of cells, antibodies that fight the
current infection, and memory cells that remain behind after the infection has been eradicated, to pump out more antibodies
if the same virus is encountered in the future. Memory cells persist for 20 years or more, and
are not increased when the animal is re-vaccinated or re-exposed to the disease. The detection of antibodies in the bloodstream,
which is what a titer test does, tells us that process took place and that memory cells are present, but the absence of antibodies
does not mean there are no memory cells or that the dog is not immune. Veterinary immunologist Ian Tizard writes, "You
can have a negative titer and if the pet is exposed, memory cells can respond within hours to regenerate enough antibodies
for protective immunity." (Tizard, Ian R., Veterinary Immunology: An Introduction, 6th Ed, Saunders 2000.) What Titer Tests Are Good For If you can’t “top off”
your dog’s immunity to viruses with booster shots, and you can’t tell from the titer test if his or her immunity
is waning, what could a titer test possibly be good for? It takes up to 14 days for the immune
system to complete its response to a modified live virus vaccination for canine viruses. This process is called “serovonversion,”
and in the vaccination stakes, it’s the brass ring. This means the dog has formed both antibodies and memory cells to
those viruses. If you test the dog’s titer two weeks after vaccination, you can tell if he or she formed immunity to
the virus. If, however, the dog did not seroconvert after vaccination, this lets you know that
the vaccine didn’t work; that is, it did not provoke the formation of immunity. This is usually because the puppy was
too young, and his or her mother’s immunity was still present at a high enough level to prevent successful immunization.
(Puppies acquire temporary immunity from their mothers after birth.) In an adult dog or much
older puppy, the reasons that vaccination fails to provoke immunity are usually related to the use of improperly stored, handled,
shipped, or administered vaccines. Very rarely, the puppy or dog has a defective immune system and is incapable of seroconverting.
Titer tests are also very useful to breeders and the owners of young puppies. They can be used
to help you customize an effective but minimal vaccination program for your puppy. Although a series of vaccines is typically
given to puppies, this isn’t because a series is needed to produce an immune response. It’s done because some
puppies don’t form immunity to the first vaccination, and would be unprotected if the next in the series were not administered.
Puppies, like adult dogs, need just one vaccine that works, what immunologists call a “single immunizing dose.”
By checking your puppy’s titers two weeks after the first vaccinations are given, you can determine whether or not immunity
formed. This enables you to avoid giving further vaccines that will provide no benefit to the puppy if he or she is already
immune, as well as let you know you need to continue to protect your puppy from exposure to these diseases if it turns out
he or she did not form immunity from the first vaccinations. You do not have to wonder, worry, and guess if your puppy’s
shots worked; you can know. The Exceptions to the Rule Titer
testing is usually done in dogs for the most common and deadly canine viruses, parvovirus (CPV) and distemper (CDV). Rabies
titer testing is also done, usually for purposes of travel to foreign countries that require it. Some viruses have unusual
antibody patterns (such as FIP in cats or HIV in humans), but we do not have vaccines for any diseases of this type in dogs.
Also, bacterial antibodies differ from viral antibodies in a number of ways, and bacterial titer testing is typically done
in veterinary medicine as a means of diagnosing acute illness, not monitoring vaccine response or ongoing immunity. Should You Test? So, should you test your dog’s titers? Probably
not. Nearly all previously vaccinated adult dogs are immune to parvovirus and distemper, and the titer test isn’t going
to give you any useful information. You cannot make an immune dog “more immune” to a virus with additional vaccination,
as the previous immunity will wipe out the virus in the vaccine. There will be no increase in immunity and no benefit to the
dog. (Schultz, Ronald D., "Current and future canine and feline vaccination programs", Veterinary Medicine, March
1998.) If a titer test will give you peace of mind, or help you make a vaccination decision about a puppy or a dog of unknown
vaccine history, then it’s worth considering. But for most owners of well-vaccinated adult dogs, neither re-vaccination
nor titer testing for parvovirus and distemper are necessary.
___________________________________________________________________________________________________________________________________
NOTE: Although vaccines licensed by the USDA
are currently available in the United States, routine vaccination of dogs against canine coronavirus and Giardia
lamblia is NOT recommended. ________________________________________________
Vaccines
I give written instuctions when to give the next vaccines
after the first set at 8 weeks. It is important to adhere to that.
DO NOT HAVE YOUR VET GIVE VACCINES ANY EARILER
THAN 3 WEEKS AFTER THE FIRST SET AT 8 WEEKS. FOLLOW THIS:
8 WEEKS-PARVO AND DISTEMPER, 12 WEEKS REPEAT PLUS BORDATELLA
AND ADENOVIRUS 2, 16 WEEKS REPEAT.
READ THE INFO BELOW. TOO MANY VACCINES ARE GIVEN
AND MAY CAUSE MORE HARM THAN GOOD.
IT IS ALSO A GOOD IDEA TO KEEP A SMALL BOTTLE OF BENADRYL
LIQUID IN YOUR PURSE AT ALL TIMES FOR THAT EMERGENCY THAT NEVER HAPPENS. IT JUST MIGHT SAVE YOUR DOGGIES LIFE. BEE STINGS,
VACCINES, POISONOUS PLANTS ETC.
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The most important immunity
is the mothers colostrum.
After this immunity has lowered in the pup, vaccines,
live or killed, have different effects on the age of the pup. see the link below.
click the address above for excellent testing and controls of the
Parvo Vaccine in puppies. Great for breeders to know what vaccine to buy and what age to give.
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Canine Diseases... What are they?
Parvo
Parvo viruses are extremely resistant to inactivation and can persist in the environment for years. They
are also resistant to most commonly used disinfectants. The virus is spread in the feces which contaminates the environment.
It can be transported on the hair or feet of infected dogs as well as on the hands and shoes of people. Dogs become infected
by ingesting the virus which then attacks the intestinal tract, white blood cells, and in very young dogs, heart muscle. Common
symptoms include severe diarrhea (bloody), vomiting, listlessness, depression, loss of appetite, and high fever. Some infected
pups get very sick, very quickly, with the only symptoms seen being severe depression, gasping for breath and sudden death.
Left untreated, many pups will die within 48 to 72 hours after onset of symptoms. This disease is highly contagious and once
established in a kennel it can be very difficult to eliminate. Treatment for Parvovirus includes correcting dehidration and
electrolyte imbalances along with hospitalization. Treating the environment with a 10% or greater chlorine bleach solution
is effective but harsh. I give my shots at 8-12 and 16 weeks or after 21 weeks, then a yearly booster and that is it.
I now do titers to see if they have immunity to these diseases below. I do not give Lepto or Corona. Always give
ORAL Benadryl 15 minutes before any vaccine. Always stay at the vets office 30 minutes after vaccines, especially RABIES.
Corona virus is a much less severe gastro-intestinal disease
then parvovirus and it causes disease primarily in puppies. Some puppies can get both corona and parvo at the same time, and
in these pups, the disease is very severe. The primary symptoms include fever, depression, vomiting and diarrhea. Puppies
infected with corona virus alone, will tend to recover within several days. Some dogs will continue to carry corona virus
without showing any symptoms, and these dogs will be a source of infection to other dogs within the kennel. Treatment includes
management of fluid and electrolyte balance.
I don't give this vaccine at all. Talk with your vet,
Leptospirosis
Leptospirosis is caused by a bacteria which is shed in the urine of infected animals. Transmission occurs
through direct contact with the skin or oral mucous membranes. Leptospirosis infects many different species of animals including
people. The disease can vary a lot in severity but common symptoms include high fever, depression, jaundice, bleeding, vomiting,
and lower back pain. It can lead to serious kidney disease with decreased urine volume, collapse and death. There are several
different serovars of Leptospirosis which can infect dogs some are spread by rodents, others by wildlife and livestock. Treatment
consists of antibiotics, fluid replacement and controlling the vomiting. An untreated animal that recovers can become
a carrier and shed the disease for up to a year. There are four strains of Leptospirosis.
I do not give this vaccine. Check with your vet if it is
needed at all.
Bordetellosis-Kennel Cough
Bordetella bronchiseptica is the most common bacteria isolated from dogs with respiratory disease. It is also a major
component of a disease commonly called Kennel Cough. Viruses such as adenovirus type 2 and parainfluenza may also play a part
in this disease. Bordetella causes a respiratory infection that is spread by breathing in respiratory secretions from coughing,
infected dogs. The most common symptom is a dry, hacking, nonproductive cough which can be followed by gagging or retching.
The cough usually lasts 1 to 3 weeks but it can take months for infected dogs to completely eliminate the bacteria from their
lungs. Infected dogs need to be immediately isolated from other dogs. Depending on the severity of their disease they may
need to be treated with antibiotics and cough suppressants. Thoroughly disinfect their cages, food and water bowls and anything
else they have been in contact with. Common disinfectants such as Chlorhexiderm are usually effective in killing these organisms.
Always make sure that kennels are properly ventilated to reduce the risk of transmission. Nebulization therapy may also be
of great help in treating these dogs. This requires a vaporizer which may or may not be used with medication.There are two
types of vaccines that are available, those that are injected and those that are given intranasally (up the nose). Injectable
vaccines can be easier to administer but intranasal vaccines act faster and produce an immunity at the level of the lining
of the respiratory tract. Antibodies are produced that prevent these organisms from gaining entry into the body.
I give the nasal vaccine at 12 and 16 weeks.
Hepatitis-Adenovirus Type I
Infectious
Canine Hepatitis is caused by Type 1 adenovirus, which is fairly resistant to inactivation. The virus that attacks the tonsils,
lymph nodes and then the liver. It is shed in all body secretions, but more commonly by urine. Transmission is by contact
with contaminated objects. This virus does not cause human hepatitis. The most common symptoms are fever, depression, abdominal
pain, vomiting and diarrhea. In a small number of infected dogs, the virus can localize in the eye, causing a whiteness or
cloudiness of the eye. Vaccines are available which can effectively prevent this disease. Most of the vaccines, however, contain
adenovirus type 2, which still protects against type 1 infections, but eliminating possible side effects of cloudy eyes which
can be seen, rarely, with adenovirus type 1 vaccines.
Parainfluenza-Adenovirus Type II
This
virus causes a mild respiratory tract infection. It is transmitted through contact with oral and nasal secretions. Common
symptoms include fever, nasal discharge, and a dry hacking cough. The disease by itself, is usually mild and brief, however,
in some cases it can progress into a more serious pneumonia. Vaccines are available to effectively prevent this disease. Two
types of canine adenovirus type 2 vaccines are available, an injectible form and also as a nasal spray, as part of a "kennel
cough" vaccine.
Given at 12 and 16 weeks
Distemper
is caused by a virus, which does not live long
outside of the dog. It is primarily transmitted by contact with respiratory secretions from an infected dog, but it can be
found in all body secretions. The disease is highly contagious and commonly causes death. The disease is most common in puppies
from 3 - 6 months of age. The initial symptoms resemble a mild cold and may even go unnoticed. Several days later, infected
dogs will have discharge from their eyes and nose, depression, loss of appetite, vomiting and diarrhea. Puppies, who survive
through the initial disease, will commonly develop seizures 1 - 3 weeks later. In most dogs the seizures will get progressively
worse, until the puppy succumbs to the disease. Puppies who survive may have incomplete development of their teeth, thickened
footpads and may develop seizures later in life. Distemper should be treated by a veterinarian. The best prevention is vaccination.
I
give bordatella bronchiseptica, parainfluenza live,
and Adenovirus Type 2, Intranasal route,
at 12 and 16 weeks
I worm my puppies AND the mother with Nemex 2, bi-weekly until they are 6 weeks, then I worm
with Ivermectin, at 6 weeks and 8 weeks. If you continue with Ivermectin, it will kill all parasites (except tapeworms), guard
against demodectic mange, and guard against heartworms. Please let your vet know that i wormed with oral Ivermectin and get
his advise.
Breeding Mother
The mother needs to be de-wormed before she is bred and 2 weeks before
she is due. If parasites are present in large amounts in the mother, the puppies are sure to have them within 2 days!
The mother will also have lower colostrum immunities in her milk to guard against the #1 killer in puppies, Parvo Virus.
RABIES VACCINE-LICENSES
Another vaccine reaction from a Rabies shot
Hi Cyndi:
I have been meaning to write you and time has gotten away! I will send more pics of course! He is still
the best dog ever!!
His rabies reactions were not as immediate. He was fine for about an hour after the shot-a little groggy
but overall ok So I went to work and when I got home that evening, his eyes were bloodshot and he didn't seem like he felt
well. My roomate had said he threw up earlier. He didn't seem interested in eating either. After a little cuddle time and
petting, he seemed like himself-ate his dinner and was playing. That night I put him in his crate like normal and went to
bed. At three in the morning he was howling in his crate, so I thought he needed to go outside. I let him out, we went outside
and he didn't go the bathroom. We came back inside and I let him get in bed with me-he started rolling around like crazy like
he was trying to furiously scratch himself. He shot to the end of the bed so I let him back outside at which point he peed
on the deck instead of the grass, then came inside and started throwing up. He had a grey look to him, he was so swollen and
it looked as if bumps had raised over his entire body. thats when i got scared and went to the emergency room. they put him
on benydryl drip and kept him for 12 hours.
Of course he was lathargic for a couple days, but now he his fine!
I did read that you are possibly breading a for a black litter for June. Adam and I would love to get on
the reservation list for that if you are!
thanks
sara
What were Rambo's reactions?? How soon after the shot did her start with the symptoms?Too bad dogs have
to get that vaccine, I know it is a law, but so many dogs get reactions and die from it. Even Autoimmune disease problems.
One of my friends' pug, was in great health. she had her own personality, did certain things, etc. but after her shot
at age 5, she became depressed within 3 days, didn't want to walk, did not bark at the sunset anylonger. then she went
blind. She became so debilitated, they put her to sleep in 4 months time. She did not want to eat, bumped into
walls, terrible.
Send more pics!!
Cyndi
Sent: Wednesday, March 26, 2008 7:22 PM
Subject: license in Los Angles
This is what is already happening in Los
Angeles!! This is only the beginning! this is crossposted from another list.....
just got 2 phone calls today. ..I am Los Angeles
One was from a friend who has a neighbor who got a letter from animal control stating that he must show proof that his
14 YEAR old dog was spayed. If not, he would be fined. This is an older man who does not even remember where he got the
dog from, let alone who spayed her. He is so afraid now that the government is going to come take his beloved dog away from
him.
Another call from a distraught client who has a dog on seizure medication and finally has her under control. Since the
vets believe that her problem is vaccine induced, she has in the past gotten an exemption for a rabies vaccine from the vet
and sent that in with her license to the city. This year, they informed her that they would no longer accept letters from
vets exempting dogs from rabies vaccines for any reason. She would either have to risk her dog's life and get the shot or
be forced to have her house become a quarantine area and her dog never allowed to leave the property and be locked away when
anyone came over. When she called the health department to try to go over the animal licensing department, they said the same
thing. Her vet has also had several clients call and tell them the same story. The vet is going to try to see if the animal
control will take a titer and if not, they have no choice but to give the dog the shot (although they said they will give
her a half dose).
Already the effects of these laws are showing up with the people who already follow the law and are now afraid of their
animals being taken away from them or being put at risk. No wonder people go underground to try to avoid things like this
I have been given permission to forward this. This just goes to show how the exemption
for show dogs is not really going to keep anyone safe.
Again, this is from someone who lives in Los Angeles
The second dog is a dog who is currently being trained for performance events and is
being specialed in the conformation ring
Nikki
Nikki -
I just went through the licensing of my older boy Harley.
Harley turns 11 this month and his 3 year rabies shot is due by April 10th, I had his titers test done in January. I
got a notice from LA County Animal Services saying that Harley's license which I just renewed in February will expire on April
10th unless he gets a new rabies shot. When I called my local shelter they gave me the run around about how titers would
be accepted but a letter from the Vet would not. When I sent in mt paperwork, I got a letter back saying that Titers
was not acceptable but a letter from my Vet would be.
I decided it would be harder to brush me off if I went
in person. I brought everything with me, the original letter saying I needed to renew, the Vet letter saying he was
too old for rabies, the Titers result and both letters from Animal Services. I showed up and showed them the renewal
letter and then the letter from the Vet saying Harley was too old for a rabies shot. They looked at the letter, made a copy
of it and asked for a $15 payment to renew his license. Out the door in under 15 minutes.
I would advise that
your neighbor go to his nearest Shelter and take any paperwork that he has from his Vet on the spay status and a letter saying
why the dog should not get another test. It is much harder to dismiss someone in person.
On a side note,
I got Pax's license renewed at the same time. They told me that I could not get an intact license because Pax did not
have a letter from the Vet giving him a 60 day exemption. I showed them Pax's last entry from Bradshaw and they hemmed
and hawed. I finally asked to speak to the Supervisor and he gave me the license. He did tell me that it would
not be this easy next year, that due to the new Ordinance I would have to fill out several forms, have proof of why I am not
neutering and a letter from my Vet.&nb! sp; Plus my name and the dog's name would be in a "special" intact database and
I should be prepared to have an Animal Control officer visit my house.
Karen
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Dog Flu
How real is the threat?
Canine Influenza, or dog flu, is a new
respiratory disease that is infecting dogs in the U.S. It was first identified in January, 2004 in racing Greyhounds in Florida.
Since then it has spread across country infecting many dogs including show dogs and family pets.
Dog flu is caused
by a canine influenza virus. Dogs become infected by breathing in the aerosolized virus coughed up by another dog or by contact
with inanimate objects which have been contaminated by oral or nasal secretions from infected dogs. People can also carry
the virus on their hands and spread it from dog to dog. The virus does not live well outside of the dog and can be destroyed
by most common disinfectants.
If your dog is exposed to the canine influenza virus, he or she will likely become infected. Most dogs have a mild
disease that may look a lot like “kennel cough”. They can have a low grade fever, nasal discharge and a persistent
cough that may last for 10 – 21 days. Some dogs will develop a more severe form of the disease with high fever and signs
of pneumonia and they will usually require antibiotics and might even need to be hospitalized.
How can you prevent
your dog from being infected? The easiest way is eliminate exposure to other dogs. In many cases that precaution is just not
possible. If your dog is going to be exposed to other dogs, use disinfectants to clean cages, food and water bowls and other inanimate objects. If you are working with or touching other dogs, wash your hands frequently and ask others to
do the same before touching your dog. Coughing dogs or those who have been exposed to coughing dogs should be isolated so
they don’t bring home canine influenza viruses to any other dogs in your home. The incubation period for this disease
is two to five days.
At this time, there is no easy, rapid test for diagnosis and there is also no vaccine available
to protect your dog from canine influenza. While “kennel cough” vaccines are not effective in protecting against
dog flu, if your dog is going to be exposed to other dogs and at risk for canine influenza, then he or she is also at risk
for kennel cough and should be vaccinated against it.
We all hear about avian influenza and the risk that it may pose to people, so can canine influenza infect
us? The risk of this virus infecting people is really low according to the Centers for Disease Control. However, health officials
will continue to monitor this disease, just to be sure.
So how real is the threat to your dog? For most family pets
that stay at home, the risk is very low. Exposure to other dog’s increases that risk; so boarding, grooming, showing
or even playing in the park can increase the possibility for infection. But given the fact that the disease is fairly mild
in most dogs, even if your dog does become infected, the threat of serious disease is still very low.
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The materials, information, and answers provided by and through this website are not intended to replace the services
of a trained pet health care professional or to be a substitute for medical advice provided by a qualified veterinarian or
other appropriate health care professional. You should consult your own veterinarian or other appropriate health care professional
on specific medical questions, including matters requiring diagnosis, treatment, therapy or medical attention.
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Worming Schedule for Puppies, Kittens, Cats & Dogs
Worms can be one of the most common and frustrating ailments of puppies and kittens but sometimes it
can be the easiest to fix. Hookworms and roundworms are by far the most common worms found in puppies and kittens. Roundworms
compete with your pet for food and can cause malnutrition or intestinal obstruction. Hookworms live on intestinal blood and
can cause anemia.
Strategic Deworming Guidelines
Strategic deworming is a practice recommended by the
American Association of Veterinary Parasitologists (AAVP) and the Centers for Disease Control and Prevention (CDC).
Puppies •
Every 2 weeks until 3 months of age, starting at 2 weeks old. • Once a month from 3 to 6 months of age •
After 6 months, follow adult recommendations. Also after six months, use a heartworm preventative medication that is effective
against hookworms and roundworms.
Adult Dogs and Cats • Treat regularly, considering potential
exposure to parasites (example: four times a year) • A continued surveillance of parasite prevalence in your area
is recommended.
Bitches and Queens • Once prior to mating • Once at birthing • Lactating
bitches and queens should be treated concurrently with puppies and kittens.
Newly Acquired Animals Note:
Obtain the deworming history of the new pet from previous owner. • Worm Immediately; then repeat after 2 weeks, then
follow guidelines above.
The first indication that a dog or cat is infected with some type of parasite is, very often,
the presence of "something" in the dog's or cat's feces. If your dog or cat (or other pet) passes anything unusual in its
feces, SAVE IT! Your veterinarian will usually find it more helpful to "see" what was in your pet's feces than to listen
to your description of it. The best way to save such specimens is to pick them out of your pet's feces and put them into a
container containing some alcohol (rubbing alcohol works fine). The alcohol will kill and preserve the specimen.
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Canine melanoma is an aggressive form of cancer that typically appears in a dog's mouth, but also may appear in the nail
bed, foot pad or other areas. Dogs with melanomas that have gone beyond initial stages typically have a lifespan of one to five months with conventional therapies. To date, the most common treatments
for this form of cancer have been radiation and surgery.
The melanoma vaccine was developed through a partnership between Merial (11789369), Memorial Sloan-Kettering Cancer Center (MSKCC) and The Animal Medical Center (AMC) of New York.
The vaccine will initially be available for use by specialists practicing veterinary oncology and will be administered
via a new Canine Transdermal Device (needle-free) developed in conjunction with Bioject (Nasdaq: BJCT), a Portland- based research pharmaceutical device company.
This (conditional) approval is the first time that the U.S. government has approved a therapeutic vaccine
for the treatment of cancer -- in either animals or humans.
Find more details from the full report. |
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